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Why is it that, when the difference between the input voltage and the output voltage is large, the voltage is stepped down by passing through multiple DC/DC converters, for example in two stages?
ICs have a limited minimum on time, and the lowest step-down voltage is limited by this. In particular, when the switching frequency is high, the minimum on time occupies a larger fraction of the period, and a desired step-down voltage cannot be obtained. To deal with such situations, there is the method of using for example two stages to step down the voltage.